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It's funny, I was just researching this too. I have the opportunity to pickup 2012 MDX 19" in black chrome for $375 with Michelin Latitude HP 255/50/19 that all have 7/32 tread left. I wonder if 255 would be too large? I see the speedometer would be off by 2 MPH based on website wheel calculators.
These on my Silver 07 RDX. Think it would look SICK
RDX specs are correct but not sure about MDX. If they are, then you're increasing overall diameter and most likely unsprung weight at each corner. If you're worried about performance, that's a no-no. If you're just in it for the looks, then go for it.
Those look an awful lot like the 19" wheels that were an upgrade option for the 1st gen RDX. If they are the same exact wheels, then they should be 19 x 8 and you can wrap them in 245/45 - 19 tires, which make them smaller (in diameter) than the 18" setup.
I recently put 19" wheels on w/ 255/45 tires b/c I wanted to maintain the same diameter. My setup are 19" wheels w/ a 35 offset and I have no issues w/ rubbing or anything and I clear all suspensions and brake components (everything is stock).