When I open the moonroof, a lot of wind comes into the interior. It becomes very windy and very loud.

I can close it about 1/3 of the way and it helps some, but this is the windiest moonroof I have ever had.

I assume everyone else's is like this too, right?

 

With my '07 I find it's quieter and calmer if I just open the rear windows a crack. It seems like there's a lot of turbulence when the air comes in the top and can't get out.

 

Back in the old days, Honda/Acura had plastic sunroof wind deflector available as an option. It helps cutting down on the wind going inside the cabin.

 

WeatherTech makes them but hasn't released them for the new TLX yet. I'm sure if they get enough requests they will speed up development. Or perhaps the one for the Accord fits.